Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 10/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.45 |
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432492 | 0.93 | SLC6A9 (0.59) | SLC6A9KCNH2 | |
| SCHEMBL4430747 | 0.93 | SLC6A9 (0.59) | SLC6A9KCNH2 | |
| SCHEMBL5047741 | 0.91 | SLC6A9 (0.72) | SLC6A9KCNH2 | |
| SCHEMBL5042130 | 0.89 | SLC6A9 (0.66) | SLC6A9KCNH2TBK1JAK2KMT2A | |
| SCHEMBL5047424 | 0.85 | SLC6A9 (0.59) | SLC6A9KCNH2 | |
| SCHEMBL5042177 | 0.85 | SLC6A9 (0.84) | SLC6A9KCNH2 | |
| SCHEMBL5045518 | 0.84 | SLC6A9 (0.71) | SLC6A9KCNH2 | |
| SCHEMBL4423806 | 0.84 | SLC6A9 (0.71) | SLC6A9KCNH2 | |
| SCHEMBL4426509 | 0.84 | SLC6A9 (0.49) | SLC6A9KCNH2 | |
| SCHEMBL5041763 | 0.84 | SLC6A9 (0.57) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |