Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 12/20 | 0.61 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427317 | 0.99 | SLC6A9 (0.62) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT | |
| SCHEMBL4424662 | 0.97 | SLC6A9 (0.62) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT | |
| SCHEMBL5045258 | 0.88 | SLC6A9 (0.63) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT | |
| SCHEMBL5047635 | 0.85 | SLC6A9 (0.62) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT | |
| SCHEMBL4420914 | 0.85 | SLC6A9 (0.66) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT | |
| SCHEMBL4424535 | 0.84 | SLC6A9 (0.67) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT | |
| SCHEMBL4433803 | 0.84 | SLC6A9 (0.73) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL4426863 | 0.84 | SLC6A9 (0.72) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT | |
| SCHEMBL4429110 | 0.84 | SLC6A9 (0.57) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT | |
| SCHEMBL4427344 | 0.83 | SLC6A9 (0.66) | SLC6A9SLC6A5LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |