Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041880 | 1.00 | F2 (0.45) | F2KLKB1ST14F7TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5041446 | 0.99 | F2 (0.44) | F2KLKB1ST14F7TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5041454 | 0.99 | F2 (0.44) | F2KLKB1ST14F7TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5038263 | 0.91 | F2 (0.44) | F2KLKB1ST14F7TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5038265 | 0.91 | F2 (0.44) | F2KLKB1ST14F7TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5040563 | 0.87 | F7 (0.51) | F2KLKB1ST14F7TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5040562 | 0.87 | F7 (0.51) | F2KLKB1ST14F7TMPRSS6 | |
| SCHEMBL5041859 | 0.87 | PKM (0.49) | F2KLKB1ST14F7PRSS1 | |
| SCHEMBL5041852 | 0.87 | PKM (0.49) | F2KLKB1ST14F7PRSS1 | |
| Hydrochloric Acid SCHEMBL5047289 | 0.86 | PKM (0.48) | F2KLKB1ST14F7PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |