Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 11/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.53 |
| ▸ | MASP2 | O00187 | 2/20 | 0.53 |
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | F7 | P08709 | 2/20 | 0.50 |
| ▸ | F9 | P00740 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5042422 | 0.99 | PKM (0.69) | PKMTPSAB1LMNAKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5042030 | 0.99 | PKM (0.69) | PKMTPSAB1LMNAKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6469315 | 0.99 | PKM (0.69) | PKMTPSAB1LMNAKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5041923 | 0.92 | PKM (0.60) | PKMTPSAB1LMNAF2ST14 | |
| Hydrochloric Acid SCHEMBL5041927 | 0.92 | PKM (0.60) | PKMTPSAB1LMNAF2ST14 | |
| Hydrochloric Acid SCHEMBL5040864 | 0.90 | PKM (0.58) | PKMTPSAB1LMNAKMT2AF2 | |
| Hydrochloric Acid SCHEMBL5040861 | 0.90 | PKM (0.58) | PKMTPSAB1LMNAKMT2AF2 | |
| Hydrochloric Acid SCHEMBL5041631 | 0.87 | MRGPRX1 (0.57) | PKMF2F10PRSS1F7 | |
| Hydrochloric Acid SCHEMBL5041621 | 0.87 | MRGPRX1 (0.57) | PKMF2F10PRSS1F7 | |
| Hydrochloric Acid SCHEMBL5042603 | 0.87 | PKM (0.55) | PKMTPSAB1F2ST14MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | claimed |