Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.74 |
| ▸ | CNR2 | P34972 | 16/20 | 0.74 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506018 | 0.85 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4512692 | 0.80 | CNR1 (0.89) | CNR1CNR2 | |
| SCHEMBL4515592 | 0.74 | CNR1 (0.78) | CNR1CNR2HTR2AHTR2C | |
| SCHEMBL4492910 | 0.74 | CNR2 (0.69) | CNR1CNR2 | |
| SCHEMBL16404258 | 0.72 | CNR1 (0.57) | CNR1CNR2GRM5HTR2AHTR2C | |
| SCHEMBL13574358 | 0.72 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL5811642 | 0.70 | CNR1 (0.81) | CNR1CNR2 | |
| SCHEMBL4904066 | 0.69 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL6700636 | 0.69 | CNR1 (0.81) | CNR1CNR2 | |
| SCHEMBL5810035 | 0.69 | CNR1 (0.58) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438296-B1 | 1H-IMIDAZOLE DERIVATIVES HAVING CB1 AGONISTIC, CB1 PARTIAL AGONISTIC OR CB1- ANTAGONISTIC ACTIVITY | SOLVAY PHARM BV (NL) | 2008-11-26 | — | — | EP | claimed |