Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068735 | 0.86 | EPHX2 (0.35) | FAAHALDH1A1AKR1B1EPHX2VNN1 | |
| SCHEMBL5042490 | 0.86 | EPHX2 (0.35) | FAAHALDH1A1AKR1B1EPHX2VNN1 | |
| SCHEMBL5043807 | 0.84 | EPHX2 (0.38) | AKR1B1EPHX2VNN1 | |
| SCHEMBL5043811 | 0.84 | EPHX2 (0.38) | AKR1B1EPHX2VNN1 | |
| SCHEMBL5041935 | 0.84 | EPHX2 (0.38) | ALDH1A1AKR1B1EPHX2VNN1 | |
| SCHEMBL5041938 | 0.84 | EPHX2 (0.38) | ALDH1A1AKR1B1EPHX2VNN1 | |
| SCHEMBL5041085 | 0.83 | PPARA (0.38) | AKR1B1EPHX2VNN1 | |
| SCHEMBL5041087 | 0.83 | PPARA (0.38) | AKR1B1EPHX2VNN1 | |
| SCHEMBL5043438 | 0.82 | EPHX2 (0.36) | AKR1B1EPHX2VNN1 | |
| SCHEMBL5038100 | 0.82 | AKR1B1 (0.37) | AKR1B1EPHX2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |