Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | VNN1 | O95497 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068735 | 1.00 | EPHX2 (0.35) | EPHX2FAAHVNN1CARM1PRMT6 | |
| SCHEMBL5042494 | 0.86 | FAAH (0.41) | EPHX2FAAHVNN1AKR1B1ALDH1A1 | |
| SCHEMBL5043811 | 0.85 | EPHX2 (0.38) | EPHX2VNN1AKR1B1SLC1A3SLC1A2 | |
| SCHEMBL5043807 | 0.85 | EPHX2 (0.38) | EPHX2VNN1AKR1B1SLC1A3SLC1A2 | |
| SCHEMBL5041935 | 0.84 | EPHX2 (0.38) | EPHX2VNN1AKR1B1SLC1A3SLC1A2 | |
| SCHEMBL5041938 | 0.84 | EPHX2 (0.38) | EPHX2VNN1AKR1B1SLC1A3SLC1A2 | |
| SCHEMBL5041085 | 0.84 | PPARA (0.38) | EPHX2VNN1AKR1B1SLC1A3SLC1A2 | |
| SCHEMBL5041087 | 0.84 | PPARA (0.38) | EPHX2VNN1AKR1B1SLC1A3SLC1A2 | |
| SCHEMBL5043438 | 0.83 | EPHX2 (0.36) | EPHX2VNN1AKR1B1SLC1A3SLC1A2 | |
| SCHEMBL5038100 | 0.83 | AKR1B1 (0.37) | EPHX2VNN1AKR1B1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |
| US-7129238-B2 | Mandelic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-10-31 | — | — | US | disclosed |
| US-20040122057-A1 | Novel mandelic acid derivatives | HOFFMANN-LA ROCHE INC. | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122057-A1 | Novel mandelic acid derivatives | F7, F11, F9 | EPHX2 1557/4885FAAH 212/4885VNN1 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.