Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408898 | 0.93 | TSHR (0.43) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL27497374 | 0.89 | TSHR (0.46) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL1759450 | 0.87 | TSHR (0.47) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL6905569 | 0.86 | TSHR (0.44) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL5311239 | 0.86 | TSHR (0.54) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL11183541 | 0.84 | CA2 (0.46) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL28120881 | 0.83 | TSHR (0.44) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL11326788 | 0.83 | TSHR (0.44) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL7636494 | 0.83 | TSHR (0.45) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL11451455 | 0.81 | TSHR (0.44) | TSHRCYP3A4ATMTDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1297046-B1 | PRESSURE-SENSITIVE ADHESIVES EXHIBITING AN IMPROVED SHEAR STRENGTH AT ELEVATED TEMPERATURES | BAYER MATERIALSCIENCE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| EP-1164154-A1 | Pressure-sensitive adhesives with improved shearing resistance at higher temperatures | BAYER AG (DE) | 2001-12-19 | — | — | EP | disclosed |