Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 18/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038154 | 0.90 | SLC6A9 (0.80) | SLC6A9KCNH2 | |
| SCHEMBL5041633 | 0.89 | SLC6A9 (0.78) | SLC6A9KCNH2 | |
| SCHEMBL4427060 | 0.88 | SLC6A9 (0.77) | SLC6A9KCNH2 | |
| SCHEMBL4433387 | 0.87 | SLC6A9 (1.00) | SLC6A9KCNH2 | |
| SCHEMBL5042717 | 0.86 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL5043534 | 0.86 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL4432731 | 0.84 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL5047845 | 0.84 | SLC6A9 (0.74) | SLC6A9KCNH2 | |
| SCHEMBL4419780 | 0.84 | SLC6A9 (0.93) | SLC6A9KCNH2 | |
| SCHEMBL5037851 | 0.84 | SLC6A9 (0.81) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |