Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18259063 | 0.89 | — | — | |
| SCHEMBL5046638 | 0.85 | CETP (0.36) | S1PR1AGTR1AGTR2ALDH1A1L3MBTL1 | |
| SCHEMBL5043356 | 0.85 | S1PR1 (0.33) | S1PR1PIK3CDSCN2A | |
| SCHEMBL5043405 | 0.82 | SCN2A (0.31) | ALDH1A1L3MBTL1SCN2A | |
| SCHEMBL14472797 | 0.81 | S1PR1 (0.35) | S1PR1ALDH1A1L3MBTL1PIK3CDSCN2A | |
| SCHEMBL5623765 | 0.80 | CETP (0.37) | AGTR1AGTR2ALDH1A1L3MBTL1 | |
| SCHEMBL14472768 | 0.79 | SCN2A (0.45) | S1PR1L3MBTL1PIK3CDSCN2A | |
| SCHEMBL5043483 | 0.76 | ALDH1A1 (0.36) | S1PR1AGTR1AGTR2ALDH1A1L3MBTL1 | |
| SCHEMBL18259018 | 0.76 | CETP (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL15702914 | 0.75 | PIK3CD (0.38) | S1PR1L3MBTL1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-B1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |
| EP-1981342-B1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |
| EP-1981342-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | disclosed |