Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043443 | 1.00 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27517855 | 0.94 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27517850 | 0.88 | HPGD (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27536473 | 0.88 | LIMK1 (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4420397 | 0.87 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14285233 | 0.85 | LHCGR (0.56) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4427626 | 0.85 | BRAF (0.54) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6218448 | 0.81 | LHCGR (0.57) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5026183 | 0.81 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27491238 | 0.79 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886999-A2 | Bicyclic heteroaromatic compound | N.V. Organon (NL) | 2008-02-13 | — | — | EP | disclosed |