Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 16/20 | 0.82 |
| ▸ | TSHR | P16473 | 2/20 | 0.82 |
| ▸ | FSHR | P23945 | 5/20 | 0.60 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037092 | 0.94 | LHCGR (0.87) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL5038376 | 0.92 | LHCGR (0.75) | LHCGRTSHRFSHR | |
| SCHEMBL5140326 | 0.91 | LHCGR (0.73) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4326072 | 0.90 | LHCGR (1.00) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL32156160 | 0.90 | LHCGR (1.00) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4429897 | 0.88 | LHCGR (0.80) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4426360 | 0.88 | LHCGR (0.63) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4421168 | 0.86 | LHCGR (0.84) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4315364 | 0.85 | LHCGR (1.00) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4313210 | 0.84 | LHCGR (1.00) | LHCGRTSHRFSHRBRAFPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886999-A2 | Bicyclic heteroaromatic compound | N.V. Organon (NL) | 2008-02-13 | — | — | EP | disclosed |