SCHEMBL5043710

SCHEMBL5043710

CC1(C)C(C=C(Cl)Cl)C1(Cc1cccc(Oc2ccccc2)c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.54
LMNA P02545 1/20 0.54
ADRA2A P08913 1/20 0.54
CNR1 P21554 1/20 0.54
ATM Q13315 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 2/20 0.41
PTGES O14684 1/20 0.40
P2RX3 P56373 2/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
MITF O75030 1/20 0.39
POLB P06746 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
CETP P11597 1/20 0.38
FFAR1 O14842 6/20 0.38
CCR8 P51685 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9020889 1.00 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL8210825 1.00 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL11220475 0.93 TDP1 (0.48) TDP1LMNAADRA2ACNR1ATM
SCHEMBL11200747 0.91 TDP1 (0.47) TDP1LMNAADRA2ACNR1ATM
SCHEMBL23824720 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL8856826 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL5854396 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL1527657 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL1527655 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL10455373 0.90 TDP1 (0.48) TDP1LMNAADRA2ACNR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1736471-B1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES MITSUI CHEMICALS AGRO INC (JP) 2014-01-08 EP claimed
EP-0413909-B1 Agent or concentrate for the preservation of wood or wooden objects DESOWAG MATERIALSCHUTZ GMBH (DE) 1994-02-02 EP claimed
US-5192793-A Solutions or emulsions CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK RT. (HU) 1993-03-09 US claimed
US-5091183-A Mixture of 2-methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl chrysanthemate and a phenoxybenzyl ester compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-02-25 US claimed
EP-0370665-A2 Wood preservative and soil treatment composition TROY CHEMICAL CORPORATION (US) 1990-05-30 EP claimed
WO-1990000859-A1 INSECT REPELLANT NELSON & ROBERTSON PTY. LTD. (AU) 1990-02-08 WO claimed
EP-0078821-B1 TRIGLYCERIDE BASED SURFACTANTS, PROCESS FOR THE PREPARATION THEREOF AND PLANT PROTECTING COMPOSITIONS CONTAINING THE SAME CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1988-12-28 EP claimed
US-4764214-A AND QUATERNARY AMMONIUM COMPOUND DR. WOLMAN GMBH (DE) 1988-08-16 US claimed
EP-0078821-A4 TRIGLYCERIDE BASED SURFACTANTS, PROCESS FOR THE PREPARATION THEREOF AND PLANT PROTECTING COMPOSITIONS CONTAINING THE SAME. CHINOIN GYOGYSZER ES VEGYESZET (HU) 1983-09-02 EP claimed
EP-0078821-A1 TRIGLYCERIDE BASED SURFACTANTS, PROCESS FOR THE PREPARATION THEREOF AND PLANT PROTECTING COMPOSITIONS CONTAINING THE SAME. CHINOIN GYOGYSZER ES VEGYESZET (HU) 1983-05-18 EP claimed
WO-1982004055-A1 TRIGLYCERIDE BASED SURFACTANTS,PROCESS FOR THE PREPARATION THEREOF AND PLANT PROTECTING COMPOSITIONS CONTAING THE SAME CHINOIN GYOGYSZER ES VEGYESZET (HU) 1982-11-25 WO claimed
US-4299972-A Preparation of cyclopropanecarboxylic acid esters CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1981-11-10 US claimed
US-4297370-A SYNERGISTIC MIXTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-10-27 US claimed
JP-3101605-A None JP disclosed
JP-9030903-A None JP disclosed
US-10647655-B2 Method for the synthesis of permethrin BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2020-05-12 US disclosed
US-4178384-A A 3-DICHLOROVINYL-2,2-DIMETHYL CYCLOPROPANE CARBOXYLATE FMC CORPORATION (US) 1979-12-11 US disclosed
EP-0004758-A2 Insecticidal compositions, and preparation and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-10-17 EP disclosed
US-4151290-A Fungicidal 1-cycloalkylcarbonyl-3-(3,5-dihalophenyl)imidazolidine-2,4-diones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-04-24 US disclosed
US-4123549-A FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647655-B2 Method for the synthesis of permethrin NUP188, CYP2E1, AQP4 TDP1 2093/4885LMNA 2817/4885ADRA2A 4416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.