SCHEMBL9020889

SCHEMBL9020889

CC1(C)[C@@H](C=C(Cl)Cl)[C@@]1(Cc1cccc(Oc2ccccc2)c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.54
LMNA P02545 1/20 0.54
ADRA2A P08913 1/20 0.54
CNR1 P21554 1/20 0.54
ATM Q13315 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 2/20 0.41
PTGES O14684 1/20 0.40
P2RX3 P56373 2/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
MITF O75030 1/20 0.39
POLB P06746 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
CETP P11597 1/20 0.38
FFAR1 O14842 6/20 0.38
CCR8 P51685 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5043710 1.00 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL8210825 1.00 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL11220475 0.93 TDP1 (0.48) TDP1LMNAADRA2ACNR1ATM
SCHEMBL11200747 0.91 TDP1 (0.47) TDP1LMNAADRA2ACNR1ATM
SCHEMBL23824720 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL8856826 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL5854396 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL1527657 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL1527655 0.91 TDP1 (0.54) TDP1LMNAADRA2ACNR1ATM
SCHEMBL10455373 0.90 TDP1 (0.48) TDP1LMNAADRA2ACNR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376598-B1 Pyrazole compounds, and their production and use SUMITOMO CHEMICAL CO (JP) 1996-02-21 EP disclosed
US-4970222-A INSECTICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-13 US disclosed
EP-0376598-A2 Pyrazole compounds, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-07-04 EP disclosed
US-4914116-A Nitrogen-containing heterocyclic compounds, and their use as insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-04-03 US disclosed
US-4879292-A Certain-phenoxy-phenoxy-alkylene-oxy-pyrimidines or symmetrical triazines, thio-analogues thereof, having insecticidal activity SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-07 US disclosed
US-4847259-A Nitrogen-containing heterocyclic compounds, and use as insecticide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-07-11 US disclosed
EP-0128648-B1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-17 EP disclosed
US-4714706-A JUVENILE HORMONE INHIBITORS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-22 US disclosed
EP-0203798-A2 Nitrogen-containing heterocyclic compounds, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-03 EP disclosed
EP-0089115-B1 OXIME ETHERS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-05-22 EP disclosed
US-4514406-A INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-04-30 US disclosed
EP-0071463-B1 THIOLCARBAMATE COMPOUNDS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-04-10 EP disclosed
US-4486449-A INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-04 US disclosed
US-4474796-A Insecticidal substituted hydantoins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-10-02 US disclosed
EP-0116103-A1 Substituted hydantoins, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-08-22 EP disclosed
EP-0089115-A1 Oxime ethers, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-09-21 EP disclosed