Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429770 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HTTRAB9A | |
| SCHEMBL5043832 | 0.75 | ALDH1A1 (0.41) | ALDH1A1HTTRAB9APOLB | |
| SCHEMBL4423510 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HTTRAB9ACYP2C19 | |
| SCHEMBL4431372 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HTTRAB9ACYP2C19 | |
| SCHEMBL4433330 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HTTRAB9ACYP2C19POLB | |
| SCHEMBL5043603 | 0.70 | ALDH1A1 (0.43) | ALDH1A1HTTRAB9ACYP2C19POLB | |
| SCHEMBL4426605 | 0.65 | MAPT (0.45) | ALDH1A1HTT | |
| SCHEMBL4422670 | 0.63 | ALDH1A1 (0.57) | ALDH1A1HTTRAB9ACYP2C19 | |
| SCHEMBL4421560 | 0.63 | MEN1 (0.46) | ALDH1A1HTTCYP2C19POLB | |
| SCHEMBL4433703 | 0.61 | ALDH1A1 (0.41) | ALDH1A1HTTRAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723116-B1 | TETRAHYDROQUINOLINONES AND THEIR USE AS ANTAGONISTS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO KGAA (DE) | 2008-09-24 | — | — | EP | claimed |