Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.61 |
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044244 | 1.00 | F10 (0.61) | F10F2TP53HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5041040 | 0.99 | F10 (0.63) | F10F2TP53HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5041029 | 0.99 | F10 (0.63) | F10F2TP53HPGDL3MBTL1 | |
| SCHEMBL6450173 | 0.90 | F10 (0.59) | F10F2PRSS1TMPRSS15NPSR1 | |
| SCHEMBL6450166 | 0.90 | F10 (0.59) | F10F2PRSS1TMPRSS15NPSR1 | |
| Hydrochloric Acid SCHEMBL5037369 | 0.90 | F10 (0.60) | F10F2PRSS1TMPRSS15NPSR1 | |
| Hydrochloric Acid SCHEMBL5037357 | 0.90 | F10 (0.60) | F10F2PRSS1TMPRSS15NPSR1 | |
| SCHEMBL5045699 | 0.90 | F10 (0.74) | F10F2HPGDPRSS1 | |
| SCHEMBL5045716 | 0.90 | F10 (0.74) | F10F2HPGDPRSS1 | |
| Hydrochloric Acid SCHEMBL5047567 | 0.89 | F10 (0.68) | F10F2HPGDPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | claimed |