Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450173 | 1.00 | F10 (0.59) | F10CYP1A2CYP2D6CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL5037357 | 0.99 | F10 (0.60) | F10CYP1A2CYP2D6CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL5037369 | 0.99 | F10 (0.60) | F10CYP1A2CYP2D6CYP3A4MEN1 | |
| SCHEMBL5044244 | 0.90 | F10 (0.61) | F10F2PRSS1NPSR1TMPRSS15 | |
| SCHEMBL5044248 | 0.90 | F10 (0.61) | F10F2PRSS1NPSR1TMPRSS15 | |
| Hydrochloric Acid SCHEMBL5041040 | 0.90 | F10 (0.63) | F10F2PRSS1NPSR1TMPRSS15 | |
| Hydrochloric Acid SCHEMBL5041029 | 0.90 | F10 (0.63) | F10F2PRSS1NPSR1TMPRSS15 | |
| SCHEMBL5045716 | 0.88 | F10 (0.74) | F10F2PRSS1 | |
| SCHEMBL5045699 | 0.88 | F10 (0.74) | F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL5041928 | 0.87 | F10 (0.68) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |