Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334722 | 0.95 | ADORA1 (0.49) | ADORA1ADORA2BADORA2AADORA3ALDH1A1 | |
| SCHEMBL1333023 | 0.94 | ADORA1 (0.50) | ADORA1ADORA2BADORA2AADORA3ALDH1A1 | |
| SCHEMBL1333466 | 0.83 | ADORA1 (0.47) | ADORA1ADORA2BADORA2AADORA3ALDH1A1 | |
| SCHEMBL5044749 | 0.81 | ADORA1 (0.42) | ADORA1 | |
| SCHEMBL4176173 | 0.80 | ADORA1 (0.62) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1334330 | 0.80 | ADORA1 (0.44) | ADORA1ADORA2BADORA2AADORA3ALDH1A1 | |
| SCHEMBL1333191 | 0.78 | ADORA1 (0.62) | ADORA1ADORA2BADORA2AADORA3ALDH1A1 | |
| SCHEMBL4182302 | 0.78 | ADORA1 (0.59) | ADORA1ADORA2BADORA2AADORA3KMT2A | |
| SCHEMBL1333496 | 0.78 | ADORA1 (0.56) | ADORA1ADORA2BADORA2AADORA3ALDH1A1 | |
| SCHEMBL5653185 | 0.78 | ADORA1 (0.43) | ADORA1ADORA2BADORA2AADORA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636229-A4 | A1 ADENOSINE RECEPTOR ANTOGONISTS | ENDACEA INC (US) | 2008-07-30 | — | — | EP | claimed |
| EP-1636229-A2 | A1 ADENOSINE RECEPTOR ANTOGONISTS | Endacea, Inc. (US) | 2006-03-22 | — | — | EP | claimed |
| WO-2005009343-A2 | A1 ADENOSINE RECEPTOR ANTOGONISTS | ENDACEA, INC. (US) | 2005-02-03 | — | — | WO | claimed |