Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044751 | 0.81 | ADORA1 (0.48) | ADORA1 | |
| SCHEMBL1334722 | 0.75 | ADORA1 (0.49) | ADORA1 | |
| SCHEMBL1333023 | 0.74 | ADORA1 (0.50) | ADORA1 | |
| SCHEMBL5035071 | 0.63 | ADORA2B (0.45) | ADORA1 | |
| SCHEMBL1333466 | 0.62 | ADORA1 (0.47) | ADORA1 | |
| SCHEMBL4271074 | 0.61 | CHRM2 (0.45) | ADORA1 | |
| SCHEMBL23797846 | 0.60 | ADORA1 (0.46) | ADORA1 | |
| SCHEMBL4176173 | 0.60 | ADORA1 (0.62) | ADORA1 | |
| SCHEMBL1334330 | 0.60 | ADORA1 (0.44) | ADORA1 | |
| SCHEMBL1334721 | 0.59 | ADORA2B (0.35) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636229-A4 | A1 ADENOSINE RECEPTOR ANTOGONISTS | ENDACEA INC (US) | 2008-07-30 | — | — | EP | claimed |
| EP-1636229-A2 | A1 ADENOSINE RECEPTOR ANTOGONISTS | Endacea, Inc. (US) | 2006-03-22 | — | — | EP | claimed |
| WO-2005009343-A2 | A1 ADENOSINE RECEPTOR ANTOGONISTS | ENDACEA, INC. (US) | 2005-02-03 | — | — | WO | claimed |