SCHEMBL504586

SCHEMBL504586

C=CCC1(COCC2(CC=C)CCCO2)CCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504537 0.86
SCHEMBL7191657 0.79
SCHEMBL503688 0.78
SCHEMBL8676646 0.77
SCHEMBL27770456 0.76
SCHEMBL34476279 0.73 MAPT (0.31)
SCHEMBL28573462 0.73 ALDH1A1 (0.32)
SCHEMBL503714 0.71
SCHEMBL10748790 0.69
SCHEMBL2106822 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153920-B2 Synthesis of functionalized high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY 2006-12-26 US claimed
US-20050256284-A1 Synthesis of functionalized high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY 2005-11-17 US claimed
US-6867265-B2 Process for improved coupling of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-15 US claimed
US-20040127659-A1 Synthesis of functionalized high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY 2004-07-01 US claimed
EP-1359165-A1 Synthesis of high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-11-05 EP claimed
US-20030100684-A1 Process for improved coupling of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2003-05-29 US claimed
US-6566478-B1 Synthesis of high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY 2003-05-20 US claimed
US-6559240-B2 Initiating anionic polymerization of one or more conjugated diolefin using alkylsilyloxy protected lithium initiator in presence of polar modifier to form living polymer; reacting liviny polymer with tin halide and silicon halide THE GOODYEAR TIRE & RUBBER COMPANY 2003-05-06 US claimed
US-20030018154-A1 Functionalized rubbery polymer containing polysiloxane GOODYEAR TIRE & RUBBER COMPANY, THE 2003-01-23 US claimed
US-6489403-B1 CROSSLINKING BUTADIENE-STYRENE LIVING POLYMERS BY REACTING WITH COUPLERS SELECTED FROM TIN AND SILICON HALIDES IN THE PRESENCE OF LITHIUM MENTHOLATE; EFFICIENCY; POLLUTION CONTROL THE GOODYEAR TIRE & RUBBER COMPANY 2002-12-03 US claimed
US-20020099148-A1 Process for tin/silicon coupling functionalized rubbers GOODYEAR TIRE & RUBBER COMPANY, THE 2002-07-25 US claimed
US-20020068798-A1 Synthesis of tin/silicon coupled rubbery polymers HALASA ADEL FARHAN (US) 2002-06-06 US claimed
US-20020061980-A1 Process for synthesizing and coupling rubbery polymers HSU WEN-LIANG (US) 2002-05-23 US claimed
US-6140434-A POLYMERIZATION INITIATOR MIXTURE COMPRISING ORGANOLITHIUM COMPOUND, POLAR MODIFIER AND A HIGH BOILING DIALKYL CYCLOHEXANOLATE OF A GROUP IA METAL; BY-PRODUCT INHIBITION NONCONTAMINATION OF RECYCLED SOLVENT STREAM THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-10-31 US claimed
US-5906956-A POLYISOPRENE RUBBER POLYMERIZATION ACTIVATOR COMPRISING A LITHIUM COMPOUND, A SODIUM ALKOXIDE AND A POLAR MODIFIER, THE TIRE FORMED FROM THE RUBBER BLEND WITH IMPROVING TREAD TRACTION, WEAR AND ROLLING RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-05-25 US claimed
US-5677402-A USING A ORGANOLITHIUM PROMOTER AND SODIUM ALKOXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-14 US claimed
US-5654384-A USING AN LITHIUM INITIATOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-08-05 US claimed
US-5620939-A Initiative system THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-04-15 US claimed
JP-6041212-A None JP disclosed
US-4477366-A INJECTION MOLDING OF POLYURETHANES OR POLYUREAS ICI AMERICAS INC. (US) 1984-10-16 US disclosed