SCHEMBL5046134

SCHEMBL5046134

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 16/20 0.50
LGALS8 O00214 2/20 0.47
LGALS9 O00182 1/20 0.44
LGALS1 P09382 1/20 0.44
LGALS3 P17931 1/20 0.44
LGALS7; LGALS7B P47929 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12347311 0.95 SLC5A2 (0.49) SLC5A2LGALS8LGALS9LGALS1LGALS3
SCHEMBL19188686 0.92 SLC5A2 (0.52) SLC5A2LGALS8
SCHEMBL14949103 0.92 SLC5A2 (0.52) SLC5A2LGALS8
SCHEMBL23547671 0.87 TSHR (0.44) SLC5A2LGALS8TSHR
SCHEMBL26554081 0.84 TSHR (0.43) SLC5A2LGALS8TSHR
SCHEMBL4139162 0.79 SLC5A2 (0.71) SLC5A2
SCHEMBL20529512 0.79 SLC5A2 (0.71) SLC5A2
SCHEMBL19189965 0.79 SLC5A2 (0.43) SLC5A2LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL12636127 0.78 SLC5A2 (0.53) SLC5A2
SCHEMBL13370879 0.78 SLC5A2 (0.53) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365970-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof ALIGOS THERAPEUTICS, INC. (US) 2023-11-16 US disclosed
US-20230365970-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof ALIGOS THERAPEUTICS, INC. (US) 2023-11-16 US disclosed
US-20230332153-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof ALIGOS THERAPEUTICS, INC. (US) 2023-10-19 US disclosed
US-20230332153-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof ALIGOS THERAPEUTICS, INC. (US) 2023-10-19 US disclosed
US-11549110-B2 Modified short interfering nucleic acid (siNA) molecules and uses thereof ALIGOS THERAPEUTICS, INC. (US) 2023-01-10 US disclosed
US-20220177888-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof ALIGOS THERAPEUTICS, INC. (US) 2022-06-09 US disclosed
US-20210189392-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS ALIGOS THERAPEUTICS, INC. 2021-06-24 US disclosed
US-7368475-B2 Furanose-type bicyclic carbohydrates with biological activity KEMIN PHARMA BVBA (US) 2008-05-06 US disclosed
US-7368475-B2 Furanose-type bicyclic carbohydrates with biological activity KEMIN PHARMA BVBA (US) 2008-05-06 US disclosed
US-7368475-B2 Furanose-type bicyclic carbohydrates with biological activity KEMIN PHARMA BVBA (US) 2008-05-06 US disclosed
US-20040220251-A1 Furanose-type bicyclic carbohydrates with biological activity KEMIN PHARMA EUROPE B.V.B.A. 2004-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365970-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof NSUN2, SNRPA, SNRPF SLC5A2 2758/4885LGALS8 3537/4885LGALS9 4442/4885
US-11549110-B2 Modified short interfering nucleic acid (siNA) molecules and uses thereof NSUN2, SNRPA, SNRPF SLC5A2 2758/4885LGALS8 3537/4885LGALS9 4442/4885
US-20220177888-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof NSUN2, SNRPA, SNRPF SLC5A2 2758/4885LGALS8 3537/4885LGALS9 4442/4885
US-20040220251-A1 Furanose-type bicyclic carbohydrates with biological activity MANBA, FBP1, GALE SLC5A2 689/4885LGALS8 72/4885LGALS9 179/4885
US-20230332153-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof NSUN2, SNRPA, SNRPF SLC5A2 2758/4885LGALS8 3537/4885LGALS9 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.