Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.44 |
| ▸ | FNTB | P49356 | 10/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048240 | 0.92 | TLR7 (0.44) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL5046581 | 0.83 | PTGER2 (0.48) | LTA4H | |
| SCHEMBL6058900 | 0.83 | MEN1 (0.47) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL8272711 | 0.80 | PTGER2 (0.49) | MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL5043195 | 0.78 | TLR7 (0.47) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL5050405 | 0.78 | PTGER2 (0.48) | — | |
| SCHEMBL5046415 | 0.77 | PTGER2 (0.44) | LTA4H | |
| SCHEMBL13626587 | 0.77 | NR1H2 (0.43) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL13399073 | 0.74 | PTGER2 (0.51) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL5046930 | 0.73 | MEN1 (0.47) | FNTAFNTBPGGT1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442702-B2 | Treatment of bone disorders; carboxy derivatives | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| EP-1021410-B1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER (US) | 2006-12-27 | — | — | EP | disclosed |
| US-6498172-B1 | (3-(((4-TERT-BUTYL-BENZYL)-(PYRIDINE-3-SULFONYL)-AMINO)-METHYL) -PHENOXY)-ACETIC ACID OR SALT; TREATING SUCH AS OSTEOPOROSIS | PFIZER INC. | 2002-12-24 | — | — | US | disclosed |
| EP-1021410-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999019300-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 1999-04-22 | — | — | WO | disclosed |