Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 14/20 | 0.58 |
| ▸ | CA1 | P00915 | 14/20 | 0.58 |
| ▸ | CA2 | P00918 | 14/20 | 0.58 |
| ▸ | CA4 | P22748 | 14/20 | 0.58 |
| ▸ | CA9 | Q16790 | 14/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050274 | 0.84 | CA12 (0.58) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049391 | 0.80 | CA12 (0.70) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049443 | 0.79 | PTGER2 (0.79) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049385 | 0.79 | CA12 (0.69) | CA12CA1CA2CA4CA9 | |
| SCHEMBL7641548 | 0.78 | CA12 (0.67) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049418 | 0.77 | CA12 (0.71) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5047904 | 0.77 | CA12 (0.71) | CA12CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL5047979 | 0.77 | CA12 (0.66) | CA12CA1CA2CA4CA9 | |
| SCHEMBL4947759 | 0.75 | CA12 (0.75) | CA12CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL5050314 | 0.75 | CA12 (0.75) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442702-B2 | Treatment of bone disorders; carboxy derivatives | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |