Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.94 |
| ▸ | PPARG | P37231 | 7/20 | 0.94 |
| ▸ | PPARD | Q03181 | 7/20 | 0.94 |
| ▸ | PPARA | Q07869 | 7/20 | 0.94 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.94 |
| ▸ | TSHR | P16473 | 4/20 | 0.94 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.94 |
| ▸ | FABP4 | P15090 | 3/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | TLR2 | O60603 | 2/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.94 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.94 |
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | ESR1 | P03372 | 1/20 | 0.94 |
| ▸ | PDE4A | P27815 | 1/20 | 0.94 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL5049745 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL15612468 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL17435180 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL2304495 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL6518226 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL8157815 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL21219131 | 0.97 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25291604 | 0.97 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL25281884 | 0.97 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Lignoceric Acid SCHEMBL25290912 | 0.97 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106010732-A | Environment-friendly metalworking grinding fluid and preparation method thereof | 上海金兆节能科技有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-105524680-A | Forging mold-releasing oil based on metal oxide and preparation method thereof | SHANGHAI JINZHAO ENERGY-SAVING TECH CO LTD | 2016-04-27 | — | — | CN | claimed |
| EP-0621257-B1 | Doubly branched compounds and methods of making them | INST FRANCAIS DU PETROLE (FR) | 1997-07-30 | — | — | EP | claimed |
| US-5434282-A | Alkylation | INSTITUT FRANCAIS DU PETROLE (FR) | 1995-07-18 | — | — | US | claimed |
| US-11826859-B2 | Brazing material, brazing member, and heat exchanger | HARIMA CHEMICALS, INCORPORATED (JP) | 2023-11-28 | — | — | US | disclosed |
| US-20220314378-A1 | BRAZING MATERIAL, BRAZING MEMBER, AND HEAT EXCHANGER | HARIMA CHEMICALS, INCORPORATED (JP) | 2022-10-06 | — | — | US | disclosed |
| CN-106999408-B | Vanishing cream composition and application thereof | 欧莱雅 | 2021-06-01 | — | — | CN | disclosed |
| CN-106010732-B | Environment-friendly metal processes grinding fluid and preparation method thereof | 上海金兆节能科技有限公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-105524680-B | Forging mould oil based on metal oxide and preparation method thereof | 上海金兆节能科技有限公司 | 2018-02-09 | — | — | CN | disclosed |
| US-9492808-B2 | Absorbent fibrous structures comprising a polymeric fluid comprising a soil adsorbing agent | THE PROCTER & GAMBLE COMPANY (US) | 2016-11-15 | — | — | US | disclosed |
| CN-106010732-A | Environment-friendly metalworking grinding fluid and preparation method thereof | 上海金兆节能科技有限公司 | 2016-10-12 | — | — | CN | disclosed |
| US-20160236172-A1 | Absorbent Fibrous Structures Comprising a Soil Absorbing Agent and a Detackifier | THE PROCTER & GAMBLE COMPANY | 2016-08-18 | — | — | US | disclosed |
| EP-0621257-B1 | Doubly branched compounds and methods of making them | INST FRANCAIS DU PETROLE (FR) | 1997-07-30 | — | — | EP | disclosed |
| US-5434282-A | Alkylation | INSTITUT FRANCAIS DU PETROLE (FR) | 1995-07-18 | — | — | US | disclosed |
| EP-0621257-A1 | Doubly branched compounds and methods of making them | INSTITUT FRANCAIS DU PETROLE (FR) | 1994-10-26 | — | — | EP | disclosed |
| US-4976952-A | Hair conditioners, emulsifiers | WELLA AKTIENGESELLSCHAFT (DE) | 1990-12-11 | — | — | US | disclosed |
| US-4938950-A | Water solubility | WELLA AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| US-4931271-A | HAIR CONDITIONERS, DYES, SHAMPOOS, PERMANENT WAVES; SKIN CREAMS | WELLA AKTIENGESELLSCHAFT (DE) | 1990-06-05 | — | — | US | disclosed |
| US-4923977-A | TREATMENT OF HAIR AND SKIN | WELLA AKTIENGESELLSCHAFT (DE) | 1990-05-08 | — | — | US | disclosed |
| US-4845204-A | Cosmetic compositions on the basis of alkyl-hydroxypropyl-substituted chitosan derivatives, new chitosan derivatives and processes for the production thereof | WELLA AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |