Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3644582 | 0.80 | CES2 (0.49) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30031785 | 0.80 | CES2 (0.49) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29556924 | 0.79 | CES2 (0.47) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL993397 | 0.78 | CES1 (0.46) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17801512 | 0.76 | SMN1; SMN2 (0.50) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL30648242 | 0.75 | CES2 (0.54) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30648236 | 0.75 | CES2 (0.54) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30648237 | 0.75 | CES2 (0.54) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11300618 | 0.75 | CES2 (0.54) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1697489 | 0.75 | CES2 (0.79) | CES2CES1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004591-A1 | CYCLOPROPANES WITH CENTRAL NERVOUS SYSTEM ACTIVITY | The Research Foundation Of State University Of New York (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008127223-A1 | CYCLOPROPANES WITH CENTRAL NERVOUS SYSTEM ACTIVITY | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-10-23 | — | — | WO | disclosed |