Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808925 | 0.86 | CYP1A1 (0.40) | KDM4ERAB9AALDH1A1BACE1JUN | |
| SCHEMBL14031242 | 0.85 | CYP1A1 (0.40) | KDM4ERAB9AALDH1A1BACE1JUN | |
| SCHEMBL14049080 | 0.85 | CYP1A1 (0.40) | KDM4ERAB9AALDH1A1BACE1JUN | |
| SCHEMBL14031141 | 0.81 | CYP1A1 (0.38) | KDM4ERAB9AALDH1A1BACE1JUN | |
| SCHEMBL20488634 | 0.80 | KDM4E (0.59) | KDM4ERAB9AALDH1A1TUBB1ERN1 | |
| SCHEMBL118322 | 0.80 | KDM4E (0.54) | KDM4ERAB9AALDH1A1TUBB1ERN1 | |
| SCHEMBL1400196 | 0.77 | KDM4E (0.51) | KDM4ERAB9AALDH1A1TUBB1ERN1 | |
| SCHEMBL3221472 | 0.76 | BACE1 (0.58) | KDM4ERAB9AALDH1A1TUBB1ERN1 | |
| SCHEMBL27500190 | 0.76 | KDM4E (0.58) | KDM4ERAB9AALDH1A1TUBB1ERN1 | |
| SCHEMBL1400081 | 0.73 | KDM4E (0.45) | KDM4ERAB9AALDH1A1TUBB1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442814-B2 | 1-methoxy-2-phenyl ethenes useful for the preparation of 5-carboxaldehyde-2-3-dihydrobenzoxepines | MERCK PATENT GMBH (DE) | 2008-10-28 | — | — | US | disclosed |