Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031242 | 1.00 | CYP1A1 (0.40) | CYP1A1CYP1B1CYP1A2NFE2L2BACE1 | |
| SCHEMBL14031141 | 0.95 | CYP1A1 (0.38) | CYP1A1CYP1B1CYP1A2NFE2L2BACE1 | |
| SCHEMBL12808925 | 0.89 | CYP1A1 (0.40) | CYP1A1CYP1B1CYP1A2NFE2L2BACE1 | |
| SCHEMBL5046907 | 0.85 | KDM4E (0.51) | CYP1A1CYP1B1CYP1A2NFE2L2BACE1 | |
| SCHEMBL1400133 | 0.75 | CYP1A1 (0.39) | CYP1A1CYP1B1CYP1A2NFE2L2BACE1 | |
| SCHEMBL1400138 | 0.75 | CYP1A1 (0.39) | CYP1A1CYP1B1CYP1A2NFE2L2BACE1 | |
| SCHEMBL1400135 | 0.75 | CYP1A1 (0.39) | CYP1A1CYP1B1CYP1A2NFE2L2BACE1 | |
| SCHEMBL1824235 | 0.73 | CYP1A1 (0.68) | CYP1A1CYP1B1CYP1A2NFE2L2JUN | |
| SCHEMBL1824237 | 0.73 | CYP1A1 (0.68) | CYP1A1CYP1B1CYP1A2NFE2L2JUN | |
| SCHEMBL118322 | 0.65 | KDM4E (0.54) | CYP1A1CYP1B1CYP1A2NFE2L2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442814-B2 | 1-methoxy-2-phenyl ethenes useful for the preparation of 5-carboxaldehyde-2-3-dihydrobenzoxepines | MERCK PATENT GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20070219381-A1 | New 1-Methoxy-2-Phenyl Ethenes Useful for the Preparation of 5-Carboxaldehyde-2-3-Dihydrobenzoxepines | MERCK PATENT GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219381-A1 | New 1-Methoxy-2-Phenyl Ethenes Useful for the Preparation of 5-Carboxaldehyde-2-3-Dihydrobenzoxepines | QDPR, FPR2, CBR1 | CYP1A1 8/4885CYP1B1 9/4885CYP1A2 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.