Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 18/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835087 | 0.85 | BRD4 (0.34) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL3033397 | 0.85 | PLA2G1B (0.40) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL5050608 | 0.84 | BRD4 (0.35) | BRD4CREBBPNR1H2NR1H3CA12 | |
| SCHEMBL3034386 | 0.82 | BRD4 (0.51) | BRD4CREBBPNR1H2NR1H3CA12 | |
| SCHEMBL3044227 | 0.81 | BRD4 (0.39) | BRD4CREBBPNR1H2NR1H3CA12 | |
| SCHEMBL3046659 | 0.81 | NR1H2 (0.44) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL3044633 | 0.80 | NR1H2 (0.41) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL3043890 | 0.79 | BRD4 (0.38) | BRD4CREBBPNR1H2NR1H3CA12 | |
| SCHEMBL3041891 | 0.78 | NR1H2 (0.38) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL3047590 | 0.78 | NR1H2 (0.45) | BRD4CREBBPNR1H2NR1H3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |