Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047269 | 0.93 | MEN1 (0.37) | TBK1MEN1KMT2AATRATRIP | |
| SCHEMBL3047734 | 0.90 | VEGFA (0.40) | TBK1IDO1TDO2IDO2GPR119 | |
| SCHEMBL3046667 | 0.90 | IDO1 (0.42) | TBK1IDO1TDO2IDO2GPR119 | |
| SCHEMBL3050148 | 0.87 | CFTR (0.39) | GPR119MEN1KMT2AATRATRIP | |
| SCHEMBL3048249 | 0.86 | GAA (0.37) | TBK1ATRATRIPNR1H2 | |
| SCHEMBL3034090 | 0.85 | LTA4H (0.36) | TBK1IDO1TDO2IDO2MEN1 | |
| SCHEMBL3050701 | 0.85 | NR1H2 (0.35) | IDO1TDO2IDO2ATRATRIP | |
| SCHEMBL3051013 | 0.85 | GAA (0.39) | MEN1KMT2ANR1H2 | |
| SCHEMBL3048132 | 0.85 | NR1H2 (0.35) | IDO1TDO2IDO2ATRATRIP | |
| SCHEMBL3153122 | 0.84 | NR1H2 (0.35) | IDO1TDO2IDO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |