Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718419 | 0.90 | MLYCD (0.60) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| SCHEMBL1852987 | 0.84 | TMEM97 (0.56) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| SCHEMBL1853427 | 0.84 | TMEM97 (0.56) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| SCHEMBL28929298 | 0.84 | MLYCD (0.76) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| SCHEMBL13577932 | 0.83 | MLYCD (0.73) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| SCHEMBL6717461 | 0.82 | MLYCD (0.56) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| SCHEMBL1851364 | 0.82 | TMEM97 (0.53) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| SCHEMBL1853434 | 0.82 | TMEM97 (0.53) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| SCHEMBL1853153 | 0.82 | TMEM97 (0.53) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 | |
| Water SCHEMBL27619617 | 0.81 | TMEM97 (0.51) | TMEM97SIGMAR1MLYCDNAAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |