Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.59 |
| ▸ | DRD4 | P21917 | 5/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL62813 | 0.99 | HDAC1 (0.58) | HDAC1HDAC6DRD4AKR1B1ACHE | |
| SCHEMBL62750 | 0.93 | HDAC1 (0.60) | HDAC1HDAC6DRD4AKR1B1ACHE | |
| SCHEMBL61826 | 0.90 | DRD4 (0.61) | HDAC1HDAC6DRD4AKR1B1ACHE | |
| SCHEMBL62174 | 0.90 | HDAC1 (0.64) | HDAC1HDAC6DRD4AKR1B1ACHE | |
| SCHEMBL3806595 | 0.90 | HDAC1 (0.57) | HDAC1HDAC6DRD4AKR1B1ACHE | |
| SCHEMBL61207 | 0.90 | HDAC1 (0.56) | HDAC1HDAC6DRD4AKR1B1SLC6A5 | |
| SCHEMBL62414 | 0.90 | HDAC1 (0.56) | HDAC1HDAC6DRD4AKR1B1SLC6A5 | |
| SCHEMBL60808 | 0.90 | HDAC1 (0.56) | HDAC1HDAC6DRD4AKR1B1SLC6A5 | |
| SCHEMBL62395 | 0.89 | HDAC1 (0.54) | HDAC1HDAC6DRD4AKR1B1SLC6A5 | |
| SCHEMBL91105 | 0.88 | HDAC1 (0.55) | HDAC1HDAC6DRD4AKR1B1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108606-A1 | Carboxamide, Sulfonamide and Amine Compounds and Methods for Using The Same | RIGEL PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108606-A1 | Carboxamide, Sulfonamide and Amine Compounds and Methods for Using The Same | AK2, PRKAA1, PRKAA2 | HDAC1 753/4885HDAC6 574/4885DRD4 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.