SCHEMBL5047339

SCHEMBL5047339

Cc1csc(N)c1B(O)O

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3114636 0.76 MAPT (0.30) MAPT
SCHEMBL3784458 0.72 ALDH1A1 (0.37)
SCHEMBL5047784 0.71 MAPT (0.39) MAPT
SCHEMBL3790184 0.68
SCHEMBL5153665 0.67
SCHEMBL13545964 0.67
SCHEMBL3792755 0.65 MAPT (0.38) MAPT
SCHEMBL3781548 0.62 MAPT (0.35) MAPT
SCHEMBL190089 0.62 ALDH1A1 (0.41) MAPT
SCHEMBL944792 0.62 ALDH1A1 (0.47) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed