Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39720 | 0.87 | CYP3A4 (0.55) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL28450617 | 0.84 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1 | |
| Ammonia Solution, Strong SCHEMBL11300905 | 0.82 | LPAR3 (0.60) | CYP3A4LPAR3LPAR2LPAR1MEN1 | |
| SCHEMBL499769 | 0.81 | MEN1 (0.38) | CYP3A4LPAR3LPAR2MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL29106099 | 0.80 | LPAR3 (0.64) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL1604996 | 0.80 | MEN1 (0.54) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL31506434 | 0.80 | LPAR3 (0.64) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL258312 | 0.79 | LPAR3 (0.62) | CYP3A4LPAR3LPAR2LPAR1MEN1 | |
| SCHEMBL8060068 | 0.78 | CYP3A4 (0.46) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL258534 | 0.77 | LPAR3 (0.67) | CYP3A4LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991554-B1 | THIOPYROPHOSPHATE ORGANIC COMPOUNDS, METHOD FOR PREPARING THEREOF AND COMPOSITIONS CONTAINING THEM | C4T S C A R L (IT) | 2013-12-25 | — | — | EP | disclosed |
| EP-1991554-A1 | THIOPYROPHOSPHATE ORGANIC COMPOUNDS, METHOD FOR PREPARING THEREOF AND COMPOSITIONS CONTAINING THEM | C4T S.C. a.r.l. (IT) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007099117-A1 | THIOPYROPHOSPHATE ORGANIC COMPOUNDS, METHOD FOR PREPARING THEREOF AND COMPOSITIONS CONTAINING THEM | C4T S.C. A R.L. (IT) | 2007-09-07 | — | — | WO | disclosed |