Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5852230 | 0.93 | LPAR3 (0.54) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL5852208 | 0.91 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL5850473 | 0.91 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL8044305 | 0.91 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL8055699 | 0.85 | MEN1 (0.35) | LPAR3LPAR2MEN1KMT2ATDP1 | |
| SCHEMBL39720 | 0.85 | CYP3A4 (0.55) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL11216760 | 0.79 | TDP1 (0.45) | CYP3A4LPAR3LPAR2TSHRMEN1 | |
| SCHEMBL1604996 | 0.78 | MEN1 (0.54) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| Ammonia Solution, Strong SCHEMBL5047510 | 0.78 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL31506434 | 0.78 | LPAR3 (0.64) | CYP3A4LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018067-A | UPGRADING A CRUDE DIHYDROCARBYLTHIOPHOSPHATE PRODUCT CONTAMINATED WITH A DIHYDROCARBYLPOLYSULFIDE AND/OR A DIHYDROCARBYLCHLOROPHOSPHATE, BY TREATING WITH HYPOCHLORITE SOLUTION AND SEPARATING AN AQUEOUS PHASE FROM THE PRODUCT | ALBEMARLE CORPORATION (US) | 2000-01-25 | — | — | US | disclosed |
| US-5955626-A | Process of purifying dihydrocarbylchlorothiophosphates | ALBEMARLE CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |