Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21445759 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL1534101 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL19033143 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL5047704 | 0.82 | MAPT (0.49) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL6516183 | 0.82 | MAPT (0.61) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL15082105 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL10332487 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL29442448 | 0.80 | MAPT (0.54) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL113361 | 0.80 | MAPT (0.54) | ALDH1A1MAPK1MAPTRAB9ANPC1 | |
| SCHEMBL3290865 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893599-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006134378-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2006-12-21 | — | — | WO | disclosed |