Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 18/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826567 | 1.00 | SLC6A9 (0.47) | SLC6A9LMNASLC6A5KCNH2S1PR3 | |
| SCHEMBL1812681 | 0.83 | SLC6A9 (0.65) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL2827679 | 0.83 | SLC6A9 (0.65) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL620281 | 0.83 | SLC6A9 (0.65) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL31465294 | 0.83 | SLC6A9 (0.65) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL30782446 | 0.83 | SLC6A9 (0.65) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL2823255 | 0.82 | SLC6A9 (0.52) | SLC6A9LMNASLC6A5KCNH2S1PR3 | |
| SCHEMBL2823258 | 0.82 | SLC6A9 (0.52) | SLC6A9LMNASLC6A5KCNH2S1PR3 | |
| SCHEMBL2827895 | 0.82 | SLC6A9 (0.52) | SLC6A9LMNASLC6A5KCNH2S1PR3 | |
| SCHEMBL8261699 | 0.81 | SLC6A9 (0.57) | SLC6A9SLC6A5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |