Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974070 | 0.87 | PDE4A (0.32) | SSTR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL916534 | 0.83 | WNT3A (0.35) | SSTR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3547325 | 0.80 | GRM2 (0.32) | SSTR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL915571 | 0.78 | SSTR5 (0.33) | SSTR5 | |
| SCHEMBL3674756 | 0.78 | SSTR5 (0.35) | SSTR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3945473 | 0.78 | PDE4D (0.35) | SSTR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL918227 | 0.77 | MEN1 (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL916709 | 0.76 | PDE4D (0.34) | SSTR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3552800 | 0.76 | GRM2 (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL916594 | 0.76 | PDE4D (0.37) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948167-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007045980-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |