Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318930 | 0.75 | TSHR (0.46) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL5212 | 0.74 | — | — | |
| SCHEMBL4620125 | 0.74 | TSHR (0.63) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL28947686 | 0.73 | TSHR (0.44) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL28947688 | 0.73 | TSHR (0.44) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL17159759 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL443213 | 0.72 | — | — | |
| SCHEMBL5424 | 0.69 | — | — | |
| SCHEMBL5885 | 0.69 | — | — | |
| SCHEMBL3141011 | 0.69 | TSHR (0.50) | LMNACYP3A4GABRA1TSHRGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481973-B1 | HETEROCYCLE-BEARING ONIUM SALTS | WAKO PURE CHEM IND LTD (JP) | 2008-12-31 | — | — | EP | disclosed |