SCHEMBL5048202

SCHEMBL5048202

CC=Cc1ccc(OCC2CO2)c(OC)c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.56
ALDH1A1 P00352 7/20 0.54
MAPT P10636 6/20 0.54
HPGD P15428 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
LMNA P02545 3/20 0.54
HTT P42858 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ATM Q13315 1/20 0.53
MAPK1 P28482 1/20 0.51
KDM4E B2RXH2 3/20 0.51
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 1/20 0.48
TYR P14679 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31596324 1.00 POLB (0.56) POLBALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL11594564 1.00 POLB (0.56) POLBALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL11595073 1.00 POLB (0.56) POLBALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL11594866 0.94 MAPT (0.54) POLBALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL3129875 0.93 MAPT (0.48) POLBALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL11592641 0.88 ALDH1A1 (0.45) POLBALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL11592704 0.88 ALDH1A1 (0.45) POLBALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL17857310 0.88 TUBB1 (0.50) ALDH1A1MAPTSMN1; SMN2LMNANPSR1
SCHEMBL11592706 0.88 ALDH1A1 (0.45) POLBALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL17843669 0.86 TUBB1 (0.47) HPGDSMN1; SMN2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1158008-B1 Curable hybrid electron donor compounds containing vinyl ether NAT STARCH CHEM INVEST (US) 2008-07-30 EP disclosed
US-7326754-B2 Thermoset adhesive films HENKEL AG & CO. KGAA (DE) 2008-02-05 US disclosed
US-7326754-B2 Thermoset adhesive films HENKEL AG & CO. KGAA (DE) 2008-02-05 US disclosed
US-7326754-B2 Thermoset adhesive films HENKEL AG & CO. KGAA (DE) 2008-02-05 US disclosed
US-20060030672-A1 Thermoset adhesive films HENKEL AG & CO. KGAA (DE) 2006-02-09 US disclosed
US-20050137340-A1 Thermoset adhesive films NIKOLIC NIKOLA A (US) 2005-06-23 US disclosed
US-20030232926-A1 Thermoset adhesive films NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2003-12-18 US disclosed
EP-1362901-A2 Thermoset adhesive films National Starch and Chemical Investment Holding Corporation (US) 2003-11-19 EP disclosed