Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038085 | 0.91 | KDM4E (0.37) | BRD4CREBBPDRD4NR1H2NR1H3 | |
| SCHEMBL3037652 | 0.91 | BRD4 (0.38) | BRD4CREBBPDRD4NR1H2NR1H3 | |
| SCHEMBL3044252 | 0.91 | BRD4 (0.36) | BRD4CREBBPDRD4NR1H2NR1H3 | |
| SCHEMBL3043652 | 0.89 | HSP90AA1 (0.37) | BRD4CREBBPDRD4NR1H2NR1H3 | |
| SCHEMBL3047029 | 0.89 | NR1H2 (0.37) | BRD4CREBBPNR1H2NR1H3PARP1 | |
| SCHEMBL3048885 | 0.89 | GPR119 (0.37) | BRD4CREBBPDRD4NR1H2NR1H3 | |
| SCHEMBL3047413 | 0.88 | NR1H2 (0.36) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL3042114 | 0.88 | SMN1; SMN2 (0.39) | BRD4CREBBPNR1H2MEN1KMT2A | |
| SCHEMBL3047734 | 0.88 | VEGFA (0.40) | NR1H2 | |
| SCHEMBL3044062 | 0.87 | PARP1 (0.45) | DRD2NR1H2MEN1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1804788-A4 | DETECTION AND ANALYSIS OF OPHTHALMICALLY-RELEVANT FLUORESCENT MOLECULES | SIRION THERAPEUTICS INC (US) | 2008-05-21 | — | — | EP | disclosed |
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |
| EP-1804788-A2 | DETECTION AND ANALYSIS OF OPHTHALMICALLY-RELEVANT FLUORESCENT MOLECULES | Sirion Therapeutics, Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006047475-A2 | DETECTION AND ANALYSIS OF OPHTHALMICALLY-RELEVANT FLUORESCENT MOLECULES | SYTERA, INC. (US) | 2006-05-04 | — | — | WO | disclosed |