Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037188 | 0.98 | PARP1 (0.36) | PARP1NR1H2TBK1 | |
| SCHEMBL3037100 | 0.91 | DRD2 (0.34) | PARP1NR1H2TBK1 | |
| SCHEMBL3043944 | 0.90 | PARP1 (0.35) | PARP1NR1H2ATR | |
| SCHEMBL3052537 | 0.89 | PARP1 (0.35) | PARP1NR1H2TBK1 | |
| SCHEMBL3050277 | 0.89 | HRH3 (0.37) | NR1H2TBK1ATR | |
| SCHEMBL3039603 | 0.88 | NR1H2 (0.33) | NR1H2TBK1ATR | |
| SCHEMBL3045879 | 0.88 | HRH3 (0.38) | NR1H2ATR | |
| SCHEMBL3047269 | 0.88 | MEN1 (0.37) | NR1H2TBK1ATR | |
| SCHEMBL3052336 | 0.88 | HRH3 (0.39) | PARP1ATR | |
| SCHEMBL3044248 | 0.87 | MEN1 (0.45) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |