Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27457156 | 0.96 | KMT2A (0.56) | KMT2AL3MBTL1MAPTSMN1; SMN2DPP4 | |
| SCHEMBL5045725 | 0.87 | FFAR1 (0.47) | KMT2AL3MBTL1MAPTSMN1; SMN2PTGS1 | |
| SCHEMBL5961842 | 0.85 | PTGS1 (0.59) | KMT2ADPP4PTGS1PTGER1PTGER4 | |
| SCHEMBL28195006 | 0.82 | FFAR1 (0.46) | PTGER1PTGER4PTGER3PTGER2PPARA | |
| SCHEMBL30887010 | 0.81 | KMT2A (0.53) | KMT2ASMN1; SMN2DPP4PTGS1PTGER1 | |
| Ethane SCHEMBL28588588 | 0.81 | PTGS1 (0.57) | KMT2ADPP4PTGS1PTGER1PTGER4 | |
| SCHEMBL3437801 | 0.80 | KMT2A (0.60) | KMT2ADPP4PTGS1PTGER1PTGER4 | |
| SCHEMBL28173176 | 0.80 | DPP4 (0.54) | KMT2ASMN1; SMN2DPP4PTGS1PTGER1 | |
| SCHEMBL538512 | 0.80 | KMT2A (0.60) | KMT2ADPP4PTGS1PTGER1PTGER4 | |
| SCHEMBL5048312 | 0.80 | SLC6A2 (0.51) | KMT2ASMN1; SMN2TSHRRAB9ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885669-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | Promerus LLC (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006128097-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | PROMERUS LLC (US) | 2006-11-30 | — | — | WO | disclosed |