Ethanesulfonic Acid Amide

Ethanesulfonic Acid Amide

SCHEMBL5048716

CCCc1ccc(S(=O)(=O)NC2Cc3cc(Cl)ccc3N(Cc3ccccc3)C2)cc1.CCS(N)(=O)=O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47
HTT P42858 1/20 0.44
HDAC8 Q9BY41 1/20 0.43
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
NR1I2 O75469 1/20 0.40
TBXA2R P21731 2/20 0.39
TBXAS1 P24557 2/20 0.39
F10 P00742 1/20 0.38
KIT P10721 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL653026 0.96 FNTA (0.49) FNTAFNTBHTTHDAC8MTNR1A
SCHEMBL652931 0.89 FNTA (0.51) FNTAFNTBHTTHDAC8MTNR1A
SCHEMBL651258 0.87 FNTA (0.55) FNTAFNTBHTTHDAC8MTNR1A
SCHEMBL651334 0.84 FNTA (0.49) FNTAFNTBHTTHDAC8MTNR1A
SCHEMBL652980 0.84 FNTA (0.49) FNTAFNTBHTTHDAC8MTNR1A
Benzenesulfonamide SCHEMBL5044828 0.83 FNTA (0.47) FNTAFNTBHTTHDAC8MTNR1A
SCHEMBL651390 0.83 FNTA (0.49) FNTAFNTBHTTHDAC8MTNR1A
SCHEMBL651552 0.81 MTNR1A (0.51) FNTAFNTBHTTHDAC8MTNR1A
SCHEMBL651621 0.81 FNTA (0.50) FNTAFNTBHTTHDAC8MTNR1A
SCHEMBL654001 0.81 FNTA (0.47) FNTAFNTBHTTHDAC8MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644335-A4 TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS BRISTOL MYERS SQUIBB CO (US) 2008-06-04 EP claimed
EP-1644335-A1 TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS Bristol-Myers Squibb Company (US) 2006-04-12 EP claimed
WO-2005007628-A1 TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2005-01-27 WO claimed