Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890870 | 0.90 | GPR119 (0.69) | GPR119 | |
| SCHEMBL5048834 | 0.86 | GPR119 (0.54) | GPR119 | |
| SCHEMBL1071520 | 0.85 | GPR119 (0.67) | GPR119 | |
| SCHEMBL5048440 | 0.84 | GPR119 (0.53) | GPR119 | |
| SCHEMBL389413 | 0.81 | GPR119 (0.84) | GPR119 | |
| SCHEMBL390591 | 0.81 | GPR119 (0.67) | GPR119 | |
| SCHEMBL16384744 | 0.80 | GPR119 (0.62) | GPR119 | |
| SCHEMBL3167001 | 0.80 | GPR119 (0.57) | GPR119 | |
| SCHEMBL3672449 | 0.80 | GPR119 (0.67) | GPR119 | |
| SCHEMBL16384785 | 0.80 | GPR119 (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004157-A2 | USE OF GPR119 RECEPTOR AGONISTS FOR INCREASING BONE MASS AND FOR TREATING OSTEOPOROSIS, AS WELL AS COMBINATION THERAPY RELATING THERETO | Arena Pharmaceuticals, Inc. (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120702-A2 | USE OF GPR119 RECEPTOR AGONISTS FOR INCREASING BONE MASS AND FOR TREATING OSTEOPOROSIS, AND COMBINATION THERAPY RELATING THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | disclosed |