Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047516 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL1856431 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL6719223 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL4715831 | 0.83 | TSHR (0.60) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL4714622 | 0.83 | TSHR (0.56) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL1852856 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL1856043 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL1854689 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL4715407 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2TSHRKMT2AHTTMEN1 | |
| SCHEMBL1853214 | 0.78 | TSHR (0.43) | SMN1; SMN2TSHRKMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |