Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | GRM8 | O00222 | 3/20 | 0.47 |
| ▸ | GRM6 | O15303 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2351634 | 0.98 | GRM4 (0.46) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL4601909 | 0.79 | GRM4 (0.47) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL4601083 | 0.79 | GRM4 (0.47) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL1814154 | 0.77 | NPSR1 (0.32) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL1814156 | 0.77 | NPSR1 (0.32) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL31284547 | 0.77 | ARG1 (0.46) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL1809492 | 0.77 | NPSR1 (0.32) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL31231756 | 0.77 | ARG1 (0.46) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL23882340 | 0.77 | APP (0.32) | CYP2C9 | |
| SCHEMBL12461686 | 0.77 | APP (0.32) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220841-B1 | TRIFLUOROMETHYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2011-07-20 | — | — | EP | disclosed |
| US-7368424-B2 | Acylated nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-05-06 | — | — | US | disclosed |
| US-6861391-B1 | Trifluoromethyl-substituted spirocyclic ketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-01 | — | — | US | disclosed |