Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1E | P28566 | 3/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866289 | 0.96 | HTR1E (0.61) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL3639348 | 0.95 | MEN1 (0.59) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL14453324 | 0.95 | MEN1 (0.59) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL5051927 | 0.95 | MEN1 (0.59) | HTR1ES1PR3MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL5051899 | 0.95 | HTR1E (0.59) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL14453320 | 0.95 | MEN1 (0.59) | HTR1ES1PR3MEN1KMT2ALMNA | |
| Water SCHEMBL28154809 | 0.93 | MEN1 (0.58) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL22188704 | 0.92 | HTR1E (0.51) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL4176732 | 0.92 | HTR1E (0.51) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL67619 | 0.85 | HTR1E (0.60) | HTR1ES1PR3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948164-A1 | PHARMACEUTICAL COMPOSITIONS OF MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | claimed |
| WO-2007045979-A1 | PHARMACEUTICAL COMPOSITIONS OF MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | claimed |
| EP-4323350-A1 | ISOINDOLINONE COMPOUNDS | Monte Rosa Therapeutics AG (CH) | 2024-02-21 | — | — | EP | disclosed |