Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050321 | 0.88 | CNR2 (0.51) | CNR1SMN1; SMN2GAAACHEBACE1 | |
| SCHEMBL3605027 | 0.75 | SLC2A2 (0.58) | GAACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13307879 | 0.74 | CNR1 (0.64) | CNR1 | |
| SCHEMBL1787365 | 0.74 | CYP3A4 (0.61) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30795104 | 0.74 | CYP3A4 (0.61) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4680489 | 0.74 | CNR1 (0.60) | CNR1SMN1; SMN2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5050317 | 0.73 | CNR1 (0.67) | CNR1ALDH1A1KMT2A | |
| SCHEMBL3604671 | 0.72 | SLC2A2 (0.55) | GAACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5359424 | 0.69 | CNR1 (0.53) | CNR1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6790329 | 0.69 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1GAACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |