Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 7/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918021 | 0.77 | PI4KA (0.31) | PI4KAPI4K2BPI4K2API4KBRET | |
| SCHEMBL5049784 | 0.77 | PDE4A (0.32) | KDM4E | |
| SCHEMBL2255357 | 0.74 | DGAT1 (0.31) | DGAT1MAP4K4 | |
| SCHEMBL2254845 | 0.74 | KDR (0.31) | DGAT1KDR | |
| SCHEMBL2733281 | 0.74 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL2260101 | 0.74 | PDE5A (0.34) | PI4KAPI4K2BPI4K2API4KBDGAT1 | |
| SCHEMBL9586925 | 0.74 | PDPK1 (0.34) | NPC1ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL2254441 | 0.71 | MAP4K4 (0.33) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| SCHEMBL2254612 | 0.70 | DGAT1 (0.31) | PI4KAPI4K2BPI4K2API4KBDGAT1 | |
| SCHEMBL2733366 | 0.70 | DGAT1 (0.30) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131501-A2 | NEW ANTI-VIRAL NUCLEOSIDE ANALOGS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |