⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647422 | 1.00 | — | — | |
| Acetamide SCHEMBL4651389 | 0.88 | HTR2A (0.34) | — | |
| SCHEMBL9766521 | 0.85 | SLC6A2 (0.37) | — | |
| SCHEMBL19474284 | 0.78 | — | — | |
| SCHEMBL7256913 | 0.77 | CDK1 (0.32) | — | |
| SCHEMBL4025607 | 0.76 | — | — | |
| SCHEMBL6797745 | 0.76 | — | — | |
| SCHEMBL7741975 | 0.76 | — | — | |
| SCHEMBL13785217 | 0.76 | PRCP (0.50) | — | |
| SCHEMBL4274460 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465549-B2 | Methods for identifying agents that bind a levetiracetam binding site (LBS) or compete with LEV binding to a LBS of a synaptic vesicle protein 2 (SV2) | UCB, S.A. (BE) | 2008-12-16 | — | — | US | disclosed |
| US-20070135514-A1 | Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases | UCB, S.A. (BE) | 2007-06-14 | — | — | US | disclosed |
| EP-1625378-A4 | METHODS FOR THE IDENTIFICATION OF AGENTS FOR THE TREATMENT OF SEIZURES, NEUROLOGICAL DISEASES, ENDOCRINOPATHIES AND HORMONAL DISEASES | UCB SA (BE) | 2007-05-16 | — | — | EP | disclosed |
| EP-1625378-A2 | METHODS FOR THE IDENTIFICATION OF AGENTS FOR THE TREATMENT OF SEIZURES, NEUROLOGICAL DISEASES, ENDOCRINOPATHIES AND HORMONAL DISEASES | UCB, S.A. (BE) | 2006-02-15 | — | — | EP | disclosed |
| US-20040204388-A1 | Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases | UCB, S.A. (BE) | 2004-10-14 | — | — | US | disclosed |
| WO-2004051222-A2 | METHODS FOR THE IDENTIFICATION OF AGENTS FOR THE TREATMENT OF SEIZURES, NEUROLOGICAL DISEASES, ENDOCRINOPATHIES AND HORMONAL DISEASES | UCB, S.A. (BE) | 2004-06-17 | — | — | WO | disclosed |
| US-20040106147-A1 | Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases | UCB, S.A. | 2004-06-03 | — | — | US | disclosed |